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HEMOSTATIC AGENT FOR WOUND TREATMENT

CELOX™ is extremely effective, safe and easy to use – just pour and apply pressure. When mixed with blood, CELOX™ forms a gel-like clot. This clotting action is independent of the body’s normal clotting processes. The clotting ability of CELOX™ has been proven to work in the presence of common anti-coagulants such as warfarin and heparin. CELOX™ Pro does not burn and does not cause discoloration of the wound bed.

CHITOSAN

CELOX is made of chitosan, a compound derived from shrimp shells. Chitosan has proven antimicrobial properties and is not a procoagulant. Chitosan is broken down and absorbed through normal metabolic pathways and has an extensive history of use in vascular closure and in human cardiac surgery.

CELOX has a three year history of use in emergency, military, and retail first aid with no reported incidents. An external review was commissioned on the safety of CELOX’s ingredients in the body and concluded that CELOX was safe to use internally in surgery and that residual quantities presented no risk.

BENEFITS AND FEATURES

• Safe, effective bleeding control in seconds
• Clots blood treated with Coumadin
• Clots blood treated with Heparin
• No known side effects
• Does not discolor the wound bed
• Easy to irrigate from wound bed

TECHNICAL DATA

4g Pouch
Prefolded 8"x8" Gauze Sheet

FOR USA ONLY

celox page
LEARN ABOUT CELOX, the original temporary traumatic wound treatment comprised of absorbent hemostatic granules

celoxa page
LEARN ABOUT CELOX-A, our CELOX applicator system for deep penetrating wounds

celoxgauze page
LEARN ABOUT CELOX GAUZE, rolled gauze coated with CELOX hemostatic agent

celox trauma gauze page
LEARN ABOUT CELOX TRAUMA GAUZE, a dual purpose gauze for treating traumatic wounds and 1st and 2nd degree burns

CELOX Testimonials (click to open and close)

“Yesterday afternoon we were called to a fallen climber with an open pelvic fracture who very nearly exsanguinated and died at the bottom of the crag. The bleeding was so brisk it had completely soaked 3 large ambulance dressings. I used Celox, and it managed to control his massive external haemorrhage until he reached the hospital via air ambulance.

The Consultant receiving the patient at the hospital was very complimentary about Celox, saying it probably helped save the guys life. It worked well, did what it was supposed to do and is ideal for use in the mountain rescue environment. Since this incident several other UK mountain rescue teams are looking into carrying it in their kits.”
Dr Steve Rowe, Medical officer PDMRO and Edale MRT

“… two interesting calls where Celox made an enormous difference. First case was an 80 year old female with renovascular hypertension and need for dialysis. To make matter worse she was on Coumadin and had an extremely high blood pressure. She needed her dialysis to reduce the pressure. She developed a spontaneous bleed in her dialysis shunt. In fact it was extremely high pressure bleeding and would not stop with pressure and pressure dressing. She came to the ED with a BP of 190/70 active bleeding in her arm and an INR of 2.1. I applied Celox and a pressure dressing and 10 min later she was bloodless and after washing off the Celox she went on to dialysis.

Case two was a 48 year old male with varicose veins in his leg and foot. EMS was called after one began bleeding. Simple pressure was not very effective in stopping it. EMS applied Celox and bandaged the foot. He came to the ED with no further bleeding. Celox was washed off and he was discharged without further need for treatment.

… what a wonderful outcome to two problematic cases with a very simple solution. It is not just gunshot and stab wounds that benefit from this wonderful product, but every day events.”
Marvin Wayne, MD, FACEP, FAAEM

“I had the opportunity to use Celox for unstoppable atraumatic bleeding from an external tumor. I stripped the existing bandaging off the area, applied the Celox all the way around and over the tumor, then placed trauma dressings and applied pressure with Coban. During the transport to the hospital, no further bleeding was noted. Once at the hospital, most of the Celox was removed, but there was no blood loss. The ED staff was very impressed, as was I. This call would have definitely turned out differently with Celox. What a wonderful product!”
Eric Augustus, Critical Care Paramedic

“We had a elderly lady with a massive facial tumor who developed bleeding from her tumor at home. Fire departments responded to the scene and were not able to control bleeding. Evaluation by paramedics with the ambulance service not able to stop the bleeding with pressures either. The paramedic then chose to use Celox and with pressure the bleeding was rapidly controlled and the patient was transported to the emergency room for definitive care. The emergency department was very happy with the care provided to the patient.”
Erling Oksenholt, DO FACEP, FACOEP

“…The infant was bleeding profusely… the infant’s head had been cut severely and looked to be fatal if not treated extremely quickly. The skin was cut an inch from the center of the forehead all the way down to the middle of the ear on the left hand side. The cut was 4 - 5 inches minimum. I… then put CELOX on the wound to stop the bleeding or else the infant would die of blood loss. I then poured the CELOX onto the skin and wrapped the bandage around the infants head. I tied off the bandage and wrapped a piece of tap around the bandage to secure it. I then took my permanent marker that was supplied in the medical kit and wrote, “CELOX - Hemostatic agent - used on infant.” I gave the package of CELOX for the father to hold and give to the paramedics. At this point a Texas State Police Officer appeared at the scene and soon after the EMS crew showed. I told the State Police Officer what happened and then told the EMS. One of the EMS crew members asked how I put it on there and said that I did it properly. He also said that if I wouldn’t have rendered aid or had a medical kit to this stature on my person the infant would have best case scenario severe brain damage due to massive blood loss or worst case scenario (most likely) the bleeding would have proven fatal because infants don’t have near as much blood as adults and he had already lost a lot of blood. … If not for the product CELOX this infant would have died.”
Zachary

“Our crew was dispatched to a large caliber GSW to the chest. After isolating the right lung, both entrance and exit wounds were sealed using the Celox product. The patient was able to maintain excellent vitals through-out the transport to the receiving hospital. All staff members involved commented on the lack of blood loss present for such a significant wound. After seeing the effectiveness of this product, I recommend using Celox as the first-line in hemorrhage control agent.”
Nicholas Puff, Paramedic

“I am the medic in charge on a research ship out of Newport, OR.  Just an hour ago a man cut an artery on his scalp.  Bleeding did not stop with pressure so I took some Celox Gauze, doubled up a 12 inch piece with an a.b.d. on top.  Bleeding stopped by the time I wrapped his head up with Kerlix.  I just got this from your office in Newport for the ship. You have a top notch product and a customer for life.  Now all my medic bags will have Celox in them, at sea and home.”
Douglas A.

“Celox is without a doubt the most exciting hemostatic dressing I have had the opportunity to work with. It is extremely easy to use, almost foolproof. I believe every soldier, not just every medic, should carry Celox in their kit.”
Chris D., US Army

 

“Wanted to let you know that we used Celox in a patient with a venous stasis wound of the leg that would not stop bleeding for several days – she had a coagulopathy on top of the physical wound. We used Celox and the bleeding stopped immediately – we left it in and did not wash it out – the wound seemed to heal well, although she will likely always have the wound…”
John P. Pryor, MD, FACS

“Had a casualty in a controlled environment with deep femoral bleed.  A tourniquet was initially placed on the wound.  The wound was wiped out with Kerlix, and Celox was poured into the wound.  The tourniquet was removed, while direct pressure was applied to the wound.  After 6 minutes, pressure was removed and everything was good.”
Jason R., US Army

“Recently, I was on a hiking trip in Oregon when a member of our party was injured when he fell off a steep ravine, catching his leg on some sharp rocks at the bottom.  From what I could see, the injury was pretty severe (a compound fracture to the right shin).  There were obvious signs of bleeding, and without the product, I think the man in our party may have very well bled to death before he could have been evacuated out to a hospital.  The product was fantastic! Acting quickly, our guide applied a dose of powder onto the wound, stopping the bleeding. And with a compression bandage and an ace wrap, the man survived with only a badly broken leg.  Simply put, the product is highly recommended & w/ out it, I fear the man in our party might have bled to death without the product.  Highly recommended!!!”
E.B

“Success stories using CELOX here in Finland: A group of Finnish deer hunters met a shooting accident in the middle of [the] wilderness. One of the hunters got a severe wound by a rifle to his left arm. Many arteries broke down and the bleeding got him into shock.

When the county Volunteer Fire Brigade First Responders and ALS paramedic level ambulance crew arrived to the scene, bleeding did not stop with pressure or with a tourniquet. Their patient, about 5o yrs old hunter was getting worse. The paramedics knew there was a long evacuation time to the nearest hospital and they did not have a chance to get a Medevac by a helicopter. The IV lines and oxygen could help only a little.

It seemed their patient might die [due] to the artery bleeding. The paramedics remembered Celox, that their local EMS director just had recommended to have in the EMS equipment. They got the training for CELOX use just a week ago. The paramedics took the 35 g CELOX pouch out of their EMS bag and decided to have a try. The countryside paramedics were surprised: the severe bleeding stopped in a minute!

The patient´s condition was stabilized and he was successfully evacuated by the ALS ambulance to the nearest hospital. The surgeons were amazed. Their first reaction was how to clean the wound area. The paramedics told just to wash it away. Nice and easy, said the surgeons!”
J.L., EMS Ambulance Officer, Finland

“…The infant was bleeding profusely. I… realized that the infants head had been cut severely and looked to be fatal if not treated extremely quickly. The skin was cut an inch from the center of the forehead all the way down to the middle of the ear on the left hand side. The cut was 4 - 5 inches minimum. I approached the infant again and told the father that we need to place the skin back where it should be and then put CELOX on the wound to stop the bleeding or else the infant would die of blood loss… I then got the package of CELOX and an Abdominal wrap. I placed the skin back into place the best I could... I then poured the CELOX onto the skin and wrapped the bandage around the infants head. I tied off the bandage and wrapped a piece of tap around the bandage to secure it. I then took my permanent marker that was supplied in the medical kit and wrote, “CELOX - Hemostatic agent - used on infant.” I gave the package of CELOX for the father to hold and give to the paramedics.   [I] then told the EMS. One of the EMS crew members asked how I put it on there and said that I did it properly. He also said that if I wouldn’t have rendered aid or had a medical kit to this stature on my person the infant would have best case scenario severe brain damage due to massive blood loss or worst case scenario (most likely) the bleeding would have proven fatal because infants don’t have near as much blood as adults and he had already lost a lot of blood….If not for the product CELOX this infant would have died.”
Zachary, Arizona

"...I had the opportunity to use CELOX on numerous times on some serious wounds and was very impressed. I found it to be the easiest to use and the easiest to train people to use. It also allowed for the correct of improper placement after initial application. When I used the product I used it like it would be used in combat. We applied the CELOX, packed the wound with gauze and wrapped it up with an elastic bandage (or in some cases we did all of this with an Olaes bandage). As soon as it was wrapped, we let it go and moved on to other injuries or engaged the "enemy". It worked very well. We never held direct pressure for than 1-2 minutes..."
Ross, Retired 18-D

"...Some of my medics used CELOX a few weeks ago and were very impressed with its clotting capability. We only had one re-bleed but that was because the medic didn't actually visualize the site and simply poured the packet into the wound cavity. Repositioning the patient so the CELOX came in contact with the wounded artery solved the problem without the need for a second packet..."
Ken B., US Army

‘ ..The Celox applicator that I used was very easy. I actually primed the end of the barrel a little to make sure that it was not clogged. I inserted it about 2 inches into the wound and inserted all of its contents without any problems in about 1second. The wound was a blast injury with some major distal bleeding.  The laceration was about 7 inches in length and full thickness to the bone with major cavitation. One of the distal vessels in the leg was bleeding very badly and when I saw him he had on a tourniquet. The Celox was introduced with a bandage and the tourniquet was removed. There was no further bleeding from the wound. This was my first time using the new applicator and as I expected, it worked amazingly. The tube filled the wound deep and directly where I needed the Celox. Of course the Celox did an amazing job getting the bleeding under control and made the patient more stable, manageable and was a life saving intervention.’
J.S., Navy Seals Medic

"...We have tried the new CELOX and found it to be a really great product..."
Ian T., MD, Canada

"...I have used your product in the real world and it works great, plus the price and performance is twice that of the competitive products. I am trying hard to get my command on board but do not have any left on me to show them. I only had three packages and used them all. I I can get command on board I will be purchasing a large amount on a regular basis. am a senior medic with 1st Special Forces Group out of Okinawa, Japan..."
Bert

"...I guess I'll start off by saying I'm bad with names. I guess if it's not written on their uniform I tend to forget. I really enjoyed the presentation of the product, I will say I was skeptical, until I tried it for myself. I really love the product, to the point of most of the medics are putting a fund together, if the army wont buy it for us we will buy it ourselves. I want to thank you for bringing another product to the table that will make my job that much easier..."
M.A., Bravo 4-9 Cav

"...I can tell you right now as for myself, CELOX is without a doubt the most exciting hemostatic dressing I have had the opportunity to work with. It is extremely easy to use, almost foolproof. I believe every soldier, not just every medic should carry CELOX on their kit..."
SSG D.

"...I finally got to try CELOX and was very impressed. Had a casualty in a controlled environment with a deep femoral bleed. A tourniquet was initially placed on the wound. The wound was wiped out with Kerlix and CELOX was poured into the wound. The tourniquet was removed, whilst direct pressure was applied to the wound. After 6 minutes pressure was removed and everything was good..."
SSG(P) Jason

"...I was very pleased with this new product CELOX and the way it performed. I was even more amazed at how even with the improper application, one package was capable of treating more than one wound (three to be exact). The CELOX product not only surprised me but gave me hope that this may make it to our troops and since I noticed no heat generation by the CELOX product and the fact that even with improper application it works very well, that if applied correctly with a very serious injury it will perform as expected without the side effects..."
Chris W, Fire Dept. TX

"...Regarding CELOX, we have some results from one of the biggest hospitals in Lithuania; they tried it on a man whose hand was crushed in a car accident and they are very happy with the results as the bleeding was stopped very quickly..."
Audrius J

"...We had an elderly lady with a massive facial tumour who developed bleeding from her tumour at home. Fire departments responded to the scene and were not able to control bleeding. Evaluation by paramedics with the ambulance service not able to stop the bleeding with pressure either. The paramedic then chose to use CELOX and with pressure the bleeding was rapidly controlled and the patient was transported to the emergency room for definitive care. The emergency department was very happy with the care provided to the patient..."
E.O., Professor of Emergency Medicine and Family Medicine

"...Had a patient with leukaemia yesterday and head laceration. Older person from a nursing home. Bleeding briskly and large scalp hematoma. Medics milked out hematoma and put CELOX into the wound. Worked like a charm. Her platelet count was low but she still clotted..."
Marv


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PRODUCT LITERATURE

CELOX PRO Overview Brochure CELOX PRO Press Kit
CELOX PRO Quick Fact Sheet  

CELOX SAFETY

Position Paper on CELOX Safety

SUPPORTING DATA

A New Hemostatic Agent: Initial Life-Saving Experience With Celox (Chitosan) in Cardiothoracic Surgery, Russell W. J. Millner, MD, FRCS (CTh), Alan S. Lockhart, FRCA, Helen Bird, FRCA, Christos Alexiou, PhD, FRCS (CTh). Departments of Cardiothoracic Surgery and Cardiothoracic Anesthesia, Blackpool Victoria Hospital, Blackpool, United Kingdom. 2009.

U.S. Navy Study
An Alternative Hemostatic Dressing: Comparison of CELOX, HemCon, and QuikClot; Buddy G. Kozen, MD, LCDR, MC, USN, Sara J. Kircher, BS, RLAT, Jose Henao, MD, LCDR, MC, USN, Fermin S. Godinez, DO, Andrew S. Johnson, MD, CDR, MC, USN


PRESS

Popular Science - December 2009
Best of What's New: Health
SAM MEDICAL CELOX TRAUMA GAUZE: A Bandage for Blood and Burns.

eWorld of Trees - May 2009
Emergency First Aid Kits for Arborists and Loggers
Even if the situation isn’t particularly life threatening, proper aid can go a long way toward alleviating pain and minimizing damage.
Oregon Business Magazine - May, 2009
To your health

Though SAM Medical Products’ granular hemostatic agent, CELOX, is geared for gaping wounds in life-threatening blood loss, Steve Melia has found it handy for something a little more everyday.
grough.uk.com
Battlefield treatment helps rescuers save climber after fall
Mountain rescuers used an innovative medical treatment to help save the life of a climber at the weekend.
Law Officer-March 2008
Clotting Agents

Here’s the scoop on these lifesaving tools.
Popular Science-July 2006
Trauma Tech: The Seafood Bandage

A new powder made from shrimp stops serious bleeding fast.

PRODUCT IMAGES FOR MEDIA AND DISTRIBUTORS

CELOX Pro Images